学历

博士

研究生

学位

医学博士

研究方向

慢性病流行病学/代谢组学/机器学习/疾病预测模型构建与评估

所在学科

流行病与卫生统计学

电子邮箱

mgy@wmu.edu.cn

简历
（从大学起）

起止年月

学习院校/工作单位

专业/学位/职务

1988/09-1993/07

南京铁道医学院

预防医学系本科

2001/09-2004/07

安徽医科大学

流行病与卫生统计学

硕士

2005/09-2008/07

安徽医科大学

流行病与卫生统计学

博士

2008/08-2016/11

温州医科大学

环境与公共卫生学院

讲师、副教授

2013/04-2016/11

温州医科大学

附属眼视光医院临床与流行病学研究中心副教授

2013/12-2015/11

约翰·霍普金斯大学

流行病与生物统计学

博士后

2016/12-至今

温州医科大学

新葡的京集团350vip8888预防医学系教授

2016/12-至今

温州医科大学

附属眼视光医院临床研究中心教授

获得项目

格式：1、项目来源，项目名称（立项年份）

1. 浙江省重点研发项目，2019C03012，心血管疾病诊治新技术研究-希浦系统起博在慢性心力衰竭患者中同步化治疗的应用研究，2019/01-2022/12，250万，在研，核心参与

2. 浙江省基础公益项目，LGF19H260011，基于代谢组学和机器学习技术的糖尿病视网膜病变早期识别研究，2019/01-2021/12，10万，在研，主持

3. 温州医科大学附属眼视光医院院内重大创新项目，YNZD170452，动态网络生物标志物用于糖尿病视网膜病变代谢机制研究，2017/01-2020/12，30万，在研，主持

4. 中华人民共和国科学技术部，2016YFC1304000，基于临床生物信息学的慢阻肺危险因素、病因和发病机制研究，2017/01-2020/12，2653万，在研，核心参与

5. 温州医科大学附属眼视光医院科研启动项目，KYQD170301，基于代谢组学的糖尿病视网膜病变超早期识别研究，2016/01-2019/12，30万，在研，主持

6. 温州医科大学附属眼视光医院院内重大课题，YNZD201403，慢性闭角型青光眼合并白内障患者联合手术与分阶段手术治疗方案的随机对照临床试验，2015/07-2019/6，30万，在研，核心参与

7. 温州医科大学附属眼视光医院院内创新课题，YNCX201308，非对称性青光眼眼局部因素对于青光眼视神经损害的多因素研究，2014/01-2017/12，12万，在研，核心参与

8. 国家自然科学基金面上项目，81260413，砷暴露对儿童DNA甲基化修饰，2013/01-2016/12，50万元，已结题，参与

9. 浙江省科技厅项目，2013C33169，代谢组学技术筛选砷致健康损害敏感性标志物的应用研究，2013/01-2016/12，15万元，在研，主持，结题

10. 浙江省自然科学基金项目，Y2110454，MTHFR基因多态性对叶酸降砷疗效修饰效应的实验流行病学研究，2011/01-2014/12，10万元，已结题，主持

11. 卫生部省部共建项目，WKJ2012-2-018，MicroRNA let-7d对注意缺陷障碍发病及预后关系的研究，2013/01-2015/12，15万元，已结题，参与  

12. 国际合作课题，Short term health effects of smoking cessation and the relationship between short term health effects and chronic diseases in Chinese population from mainland China.，2013/01-2014/12，92万，已结题，核心参与

13. 国家十一·五科技支撑计划，2009BAI77B06，心理疾患防治研究与示范，2010/01-2012/12，506万元，已结题，核心参与

14. 温州市科技局面上项目，Y20090026，胃癌相关生物标志物分子流行病学研究，2009/01-2012/12，3万元，已结题，主持

发表文章

1. Wei YP, Jia CN, Lan Y, Hou XQ, Zuo JJ, Cui H, Guan XJ, Wang Y, Mao GY. Serum cholesterol positively associated with oxidative DNA damage: a propensity score-matched analysis. Free Radic Res 2019; 53(4): 411-7.（通讯作者）

2. Ren W, Qiu H, Yang Y, Zhu X, Zhu C, Mao G, Mao S, Lin Y, Shen S, Li C, Xie X, Shi H, Jiang S, Zhao K, Chen L, He J, Xu L, Fu Y, Hu X, Yu Y, Gu Y, Wang K, Guo X, He J. Randomized controlled trial of cognitive behavioural therapy for depressive and anxiety symptoms in Chinese women with breast cancer. Psychiatry Res 2019; 271: 52-9.

3. Liao N, Jiang H, Mao G, Li Y, Xue A, Lan Y, Lin H, Wang Q. Changes in macular ultrastructural morphology in unilateral anisometropic amblyopia. Am J Transl Res 2019; 11(8): 5086-95.

4. Jia C, Wei Y, Lan Y, Hou X, Zuo J, Wang T, Li J, Guan X, Yang H, Mao G. Comprehensive analysis of the metabolomic characteristics on the health lesions induced by chronic arsenic exposure: A metabolomics study. Int J Hyg Environ Health 2019; 222(3): 434-45. （通讯作者）

5. Huang W, Su L, Wu S, Xu L, Xiao F, Zhou X, Mao G, Vijayaraman P, Ellenbogen KA. Long-term outcomes of His bundle pacing in patients with heart failure with left bundle branch block. Heart 2019; 105(2): 137-43.

6. Hou X, Wang D, Zuo J, Li J, Wang T, Guo C, Peng F, Su D, Zhao L, Ye Z, Zhang H, Zheng C, Mao G. Development and validation of a prognostic nomogram for HIV/AIDS patients who underwent antiretroviral therapy: data from a China population-based cohort. Ebiomedicine (inpress) 2019. （通讯作者）

7. Yu Y, Mao G, Wang J, Zhu L, Lv X, Tong Q, Fang Y, Lv Y, Wang G. Gut dysbiosis is associated with the reduced exercise capacity of elderly patients with hypertension. Hypertens Res 2018; 41(12): 1036-44.

8. Qiu H, Ren W, Yang Y, Zhu X, Mao G, Mao S, Lin Y, Shen S, Li C, Shi H, Jiang S, He J, Zhao K, Fu Y, Hu X, Gu Y, Wang K, Guo X, He J. Effects of cognitive behavioral therapy for depression on improving insomnia and quality of life in Chinese women with breast cancer: results of a randomized, controlled, multicenter trial. Neuropsychiatr Dis Treat 2018; 14: 2665-73.

9. Guo X, Chen X, Wang J, Liu Z, Gaile D, Wu H, Yu G, Mao G, Yang Z, Di Z, Guo X, Cao L, Chang P, Kang B, Chen J, Gao W, Ren X. Multi-generational impacts of arsenic exposure on genome-wide DNA methylation and the implications for arsenic-induced skin lesions. Environ Int 2018; 119: 250-63.

10. Gao W, Huang T, Yuan H, Yang J, Jin Q, Jia C, Mao G, Zhao J. Highly sensitive detection and mutational analysis of lung cancer circulating tumor cells using integrated combined immunomagnetic beads with a droplet digital PCR chip. Talanta 2018; 185: 229-36.

11. Wu Q, Cao Y, Mao G, Wang S, Fang Y, Tong Q, Huang Q, Wang B, Yan J, Wang G. Effects of forest bathing on plasma endothelin-1 in elderly patients with chronic heart failure: Implications for adjunctive therapy. Geriatr Gerontol Int 2017; 17(12): 2627-9.

12. Mueller NT, Mao G, Bennet WL, Hourigan SK, Dominguez-Bello MG, Appel LJ, Wang X. Does vaginal delivery mitigate or strengthen the intergenerational association of overweight and obesity? Findings from the Boston Birth Cohort. Int J Obes (Lond) 2017; 41(4): 497-501.

13. Mao G, Nachman RM, Sun Q, Zhang X, Koehler K, Chen Z, Hong X, Wang G, Caruso D, Zong G, Pearson C, Ji H, Biswal S, Zuckerman B, Wills-Karp M, Wang X. Individual and Joint Effects of Early-Life Ambient Exposure and Maternal Prepregnancy Obesity on Childhood Overweight or Obesity. Environ Health Perspect 2017; 125(6): 067005.

14. Lin Z, Vasudevan B, Ciuffreda KJ, Zhou HJ, Mao GY, Wang NL, Liang YB. Myopigenic Activity Change and Its Risk Factors in Urban Students in Beijing: Three-Year Report of Beijing Myopia Progression Study. Ophthalmic Epidemiol 2017; 24(6): 388-93.

15. Lin Z, Vasudevan B, Ciuffreda KJ, Zhou HJ, Mao GY, Wang NL, Liang YB. The difference between cycloplegic and non-cycloplegic autorefraction and its association with progression of refractive error in Beijing urban children. Ophthalmic Physiol Opt 2017; 37(4): 489-97.

16. Jiang JH, Zhang SD, Dai ML, Yang JY, Xie YQ, Hu C, Mao GY, Lu F, Liang YB. Posner-Schlossman syndrome in Wenzhou, China: a retrospective review study. Br J Ophthalmol 2017; 101(12): 1638-42.

17. Hong X, Hao K, Ji H, Peng S, Sherwood B, Di Narzo A, Tsai HJ, Liu X, Burd I, Wang G, Ji Y, Caruso D, Mao G, Bartell TR, Zhang Z, Pearson C, Heffner L, Cerda S, Beaty TH, Fallin MD, Lee-Parritz A, Zuckerman B, Weeks DE, Wang X. Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth. Nat Commun 2017; 8: 15608.

18. Chen X, Guo X, He P, Nie J, Yan X, Zhu J, Zhang L, Mao G, Wu H, Liu Z, Aga D, Xu P, Smith M, Ren X. Interactive Influence of N6AMT1 and As3MT Genetic Variations on Arsenic Metabolism in the Population of Inner Mongolia, China. Toxicol Sci 2017; 155(1): 124-34.

19. Zhao T, Jin Y, Mao G, Wei Y, Wu G, Ye X, Zhou Y, Yuan G, Gao L, Hong Y, Chen Y, Hong C, Zhou H, Su D, Qin Z, Lu L. CYFRA 21-1 is an early predictor of chemotherapeutic effectiveness in advanced nonsmall cell lung cancer: An observational study. Medicine (Baltimore) 2016; 95(52): e5748.

20. Wang G, Johnson S, Gong Y, Polk S, Divall S, Radovick S, Moon M, Paige D, Hong X, Caruso D, Chen Z, Mallow E, Walker SO, Mao G, Pearson C, Wang MC, Zuckerman B, Cheng TL, Wang X. Weight Gain in Infancy and Overweight or Obesity in Childhood across the Gestational Spectrum: a Prospective Birth Cohort Study. Sci Rep 2016; 6: 29867.

21. Walker SO, Mao G, Caruso D, Hong X, Pongracic JA, Wang X. Cardiovascular Risk Factors in Parents of Food-Allergic Children. Medicine (Baltimore) 2016; 95(15): e3156.（共同第1作者）

22. Nachman RM, Mao G, Zhang X, Hong X, Chen Z, Soria CS, He H, Wang G, Caruso D, Pearson C, Biswal S, Zuckerman B, Wills-Karp M, Wang X. Intrauterine Inflammation and Maternal Exposure to Ambient PM2.5 during Preconception and Specific Periods of Pregnancy: The Boston Birth Cohort. Environ Health Perspect 2016; 124(10): 1608-15.（共同第1作者）

23. Lin Z, Vasudevan B, Mao GY, Ciuffreda KJ, Jhanji V, Li XX, Zhou HJ, Wang NL, Liang YB. The influence of near work on myopic refractive change in urban students in Beijing: a three-year follow-up report. Graefes Arch Clin Exp Ophthalmol 2016; 254(11): 2247-55.

24. Lin Z, Vasudevan B, Fang SJ, Jhanji V, Mao GY, Han W, Gao TY, Ciuffreda KJ, Liang YB. Eye exercises of acupoints: their impact on myopia and visual symptoms in Chinese rural children. BMC Complement Altern Med 2016; 16: 349.

25. Hong X, Ladd-Acosta C, Hao K, Sherwood B, Ji H, Keet CA, Kumar R, Caruso D, Liu X, Wang G, Chen Z, Ji Y, Mao G, Walker SO, Bartell TR, Ji Z, Sun Y, Tsai HJ, Pongracic JA, Weeks DE, Wang X. Epigenome-wide association study links site-specific DNA methylation changes with cow's milk allergy. J Allergy Clin Immunol 2016; 138(3): 908-11 e9.

26. Lin Z, Mao GY, Vasudevan B, Jin ZB, Ciuffreda KJ, Jhanji V, Zhou HJ, Wang NL, Liang YB. The Association between Maternal Reproductive Age and Progression of Refractive Error in Urban Students in Beijing. PLoS One 2015; 10(9): e0139383.

27. Li J, Jiang S, Zhang Y, Tang G, Wang Y, Mao G, Li Z, Xu X, Wang B, Huo Y. H-type hypertension and risk of stroke in chinese adults: A prospective, nested case-control study. J Transl Int Med 2015; 3(4): 171-8.

28. Guo X, Cui H, Zhang H, Guan X, Zhang Z, Jia C, Wu J, Yang H, Qiu W, Zhang C, Yang Z, Chen Z, Mao G. Protective Effect of Folic Acid on Oxidative DNA Damage: A Randomized, Double-Blind, and Placebo Controlled Clinical Trial. Medicine (Baltimore) 2015; 94(45): e1872.（通讯作者）

29. Zhou LL, Zhang X, Bao QQ, Liu RP, Gong MY, Mao GY, Zou M, Zhu JH. Association analysis of PARK16-18 variants and Parkinson's disease in a Chinese population. J Clin Neurosci 2014; 21(6): 1029-32.

30. Yang H, Mao G, Zhang H, Zhang C, Qiu W, Guo X. [Association between dyslipidemia and 8-OHdG/Cr among a population exposed to chronic arsenic]. Zhonghua Liu Xing Bing Xue Za Zhi 2014; 35(7): 802-5.

31. Wang Y, Huang XF, Yang MM, Cai WJ, Zheng MQ, Mao G, Pang CP, Jin ZB. CFI-rs7356506 is a genetic protective factor for acute anterior uveitis in Chinese patients. Br J Ophthalmol 2014; 98(11): 1592-6.

32. Luo P, Wu J, Mao GY. Pedicle screw fixation in minimally invasive transforaminal lumbar interbody fusion. Neurosurg Focus 2014; 36(6): 1.

33. Lin Z, Vasudevan B, Jhanji V, Mao GY, Gao TY, Wang FH, Rong SS, Ciuffreda KJ, Liang YB. Near work, outdoor activity, and their association with refractive error. Optom Vis Sci 2014; 91(4): 376-82.

34. Lin Z, Gao TY, Vasudevan B, Jhanji V, Ciuffreda KJ, Zhang P, Li L, Mao GY, Wang NL, Liang YB. Generational difference of refractive error and risk factors in the Handan Offspring Myopia Study. Invest Ophthalmol Vis Sci 2014; 55(9): 5711-7.

35. Zhang C, Mao G, He S, Yang Z, Yang W, Zhang X, Qiu W, Ta N, Cao L, Yang H, Guo X. Relationship between long-term exposure to low-level arsenic in drinking water and the prevalence of abnormal blood pressure. J Hazard Mater 2013; 262: 1154-8.（共同第1作者）

36. Hu H, Cui H, Han W, Ye L, Qiu W, Yang H, Zhang C, Guo X, Mao G. A cutoff point for arterial stiffness using the cardio-ankle vascular index based on carotid arteriosclerosis. Hypertens Res 2013; 36(4): 334-41.（通讯作者）

37. Jiang Z, Shen M, Mao G, Chen D, Wang J, Qu J, Lu F. Association between corneal biomechanical properties and myopia in Chinese subjects. Eye (Lond) 2011; 25(8): 1083-9.

38. Mao G, Guo X, Kang R, Ren C, Yang Z, Sun Y, Zhang C, Zhang X, Zhang H, Yang W. Prevalence of disability in an arsenic exposure area in Inner Mongolia, China. Chemosphere 2010; 80(9): 978-81.

39. Zhang X, Mao GY, Liu HP, Xu XP. [Influence of blood pressure lowering treatment on IPSS, Qmax in old and middle-aged male patients with essential hypertension]. Zhonghua Nan Ke Xue 2009; 15(7): 632-5.

40. Liu H, Liu P, Mao G, Chen G, Wang B, Qin X, Na Y, Liu Z, Wang X, Xu X. Efficacy of combined amlodipine/terazosin therapy in male hypertensive patients with lower urinary tract symptoms: a randomized, double-blind clinical trial. Urology 2009; 74(1): 130-6.

41. Fu J, Tang HQ, Qin XH, Mao GY, Tang GF. [Efficacy of enalapril combined with folic acid in lowering blood pressure and plasma homocysteine level]. Zhonghua Yi Xue Za Zhi 2009; 89(31): 2179-83.

42. Mao G, Hong X, Xing H, Liu P, Liu H, Yu Y, Zhang S, Jiang S, Wang X, Xu X. Efficacy of folic acid and enalapril combined therapy on reduction of blood pressure and plasma glucose: a multicenter, randomized, double-blind, parallel-controlled, clinical trial. Nutrition 2008; 24(11-12): 1088-96.

43. Liu H, Zhang S, Jiang S, Mao G, Hong X, Yu Y, Zhang Y, Tang G, Xing H, Xu X. Renin-angiotensin-aldosterone system gene polymorphisms and antihypertensive response to irbesartan in Chinese hypertensives. Methods Find Exp Clin Pharmacol 2008; 30(4): 307-12.

44. Feng Y, Mao G, Ren X, Xing H, Tang G, Li Q, Li X, Sun L, Yang J, Ma W, Wang X, Xu X. Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. Diabetes Care 2008; 31(10): 1939-44.（共同第1作者）

45. Wang X, Qin X, Demirtas H, Li J, Mao G, Huo Y, Sun N, Liu L, Xu X. Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet 2007; 369(9576): 1876-82.

46. Chen G, Jiang S, Mao G, Zhang S, Hong X, Tang G, Li Z, Liu X, Zhang Y, Xing H, Wang B, Yu Y, Xu X. CYP2C9 Ile359Leu polymorphism, plasma irbesartan concentration and acute blood pressure reductions in response to irbesartan treatment in Chinese hypertensive patients. Methods Find Exp Clin Pharmacol 2006; 28(1): 19-24.

47. Zhang S, Mao G, Zhang Y, Tang G, Wen Y, Hong X, Jiang S, Yu Y, Xu X. Association between human atrial natriuretic peptide Val7Met polymorphism and baseline blood pressure, plasma trough irbesartan concentrations, and the antihypertensive efficacy of irbesartan in rural Chinese patients with essential hypertension. Clin Ther 2005; 27(11): 1774-84.

48. Jiang S, Mao G, Zhang S, Hong X, Tang G, Li Z, Liu X, Zhang Y, Wang B, Xu X, Wang X. Individual and joint association of alpha1A-adrenergic receptor Arg347Cys polymorphism and plasma irbesartan concentration with blood pressure therapeutic response in Chinese hypertensive subjects. Clin Pharmacol Ther 2005; 78(3): 239-48.

49. Hong X, Zhang S, Mao G, Jiang S, Zhang Y, Yu Y, Tang G, Xing H, Xu X. CYP2C9*3 allelic variant is associated with metabolism of irbesartan in Chinese population. Eur J Clin Pharmacol 2005; 61(9): 627-34.

荣誉及人才称号
（校级及以上）

浙江省高校中青年学科带头人

温州市551人才

校级优秀共产党员

温州医科大学师德标兵

学术兼职

全国工业统计学教学研究会健康医疗大数据学会  常务理事

中国医药教育协会健康管理专业委员会  常务委员

中国医疗保健国际交流促进会循证医学分会临床研究学组  副组长

中国医师协会循证医学专业委员会循证眼科分会  委员

中国卫生信息学会卫生统计教育专业委员会  委员

中国卫生信息学会统计理论与方法专业委员会  委员

中国医药教育协会医药统计专业委员会  委员

浙江省抗癌协会肿瘤流行病学专业委员会  委员

浙江省预防医学会流行病学专业委员会  委员

安徽省预防医学会卫生统计专业委员会  常务委员